To draw, pull, or move suddenly and sharply; jerk: I twitched my fishing line. To move jerkily or spasmodically. See Synonyms at jerk1. To ache sharply from time to time; twinge. A sudden involuntary or spasmodic muscular movement: a twitch of the eye. A sudden pulling; a tug: The fish gave my line a twitch. A looped cord used to restrain a horse by tightening it around the animal's upper lip.