From then until now or between then and now: They left town and haven't been here since. Before now; ago: a name long since forgotten. After some point in the past; at a subsequent time: My friend has since married and moved to California. Continuously from: They have been friends since childhood. Intermittently from: She's been skiing since childhood. During the period subsequent to the time when: He hasn't been home since he graduated. Continuously from the time when: They have been friends ever since they were in grade school. Inasmuch as; because: Since you're not interested, I won't tell you about it.