Qué es science? Qué es science? The observation, identification, description, experimental investigation, and theoretical explanation of phenomena.Such activities restricted to a class of natural phenomena.Such activities applied to an object of inquiry or study. Methodological activity, discipline, or study: I've got packing a suitcase down to a science. An activity that appears to require study and method: the science of purchasing. Knowledge, especially that gained through experience.Christian Science.