Of or relating to a large geographic region. Of or relating to a particular region or district. Of or affecting a region of the body: regional pain. Of or characteristic of a form of a language that is distributed in identifiable geographic areas and differs in pronunciation, grammar, or vocabulary from the standard form; dialectal. Something, such as a magazine or a company branch, that serves a region: "earlier attempts to launch glossy regionals for women\u201d ( Business Week).