Of or relating to the nerves or nervous system: nervous tissue. Stemming from or affecting the nerves or nervous system: a nervous disorder. Easily agitated or distressed; high-strung or jumpy. Marked by or having a feeling of unease or apprehension: nervous moments before takeoff. Vigorous in style or feeling; spirited: "the nervous thrust of a modern creation\u201d ( Henry A. Kissinger). Archaic Strong; sinewy.