Existing in or belonging to one by nature; innate: native ability. Being such by birth or origin: a native Scot. Being one's own because of the place or circumstances of one's birth: our native land. Originating, growing, or produced in a certain place or region; indigenous: a plant native to Asia. Being a member of the original inhabitants of a particular place. Of, belonging to, or characteristic of such inhabitants: native dress; the native diet of Polynesia. Occurring in nature pure or uncombined with other substances: native copper. Natural; unaffected: native beauty. Archaic Closely related, as by birth or race. Biochemistry Of or relating to the naturally occurring conformation of a macromolecule, such as a protein. One born in or connected with a place by birth: a native of Scotland now living in the United States. One of the original inhabitants or lifelong residents of a place. An animal or plant that originated in a particular place or region.