To mix together, especially confusedly: The various flavors are muddled in this recipe. To mix (a drink or the ingredients of a drink), especially with a muddler. To put into a state of confusion; confuse: Emotional rhetoric will only muddle the debate on the issue. To confuse or befuddle (a person or the mind, for example). See Synonyms at befuddle. To mismanage or bungle: muddle a task. To make turbid or muddy. A disordered condition; a mess or jumble. A state of mental confusion. See muddler.