To make or process (a raw material) into a finished product, especially by means of a large-scale industrial operation. To make or process (a product), especially with the use of industrial machines. To create, produce, or turn out in a mechanical manner:"His books seem to have been manufactured rather than composed"(Dwight Macdonald). To concoct or invent; fabricate: manufacture an excuse. The act, craft, or process of manufacturing products, especially on a large scale. An industry in which mechanical power and machinery are employed. A product that is manufactured. The making or producing of something.