The act or an instance of flowing, passing, or giving out. The act of circulating, distributing, or publishing by an office or official group: government issue of new bonds. Something produced, published, or offered, as: An item or set of items, as stamps or coins, made available at one time by an office or bureau. A single copy of a periodical: the May issue of the magazine. A distinct set of copies of an edition of a book distinguished from others of that edition by variations in the printed matter. A final result or conclusion, as a solution to a problem. Proceeds from estates or fines. Something proceeding from a specified source: suspicions that were the issue of a deranged mind. Offspring; progeny: died without issue. A point or matter of discussion, debate, or dispute: legal and moral issues. A matter of public concern: debated economic issues. A misgiving, objection, or complaint: had issues with the plan to change the curriculum. The essential point; crux: the issue of how to provide adequate child care. A culminating point leading to a decision: bring a case to an issue. Informal A personal problem or emotional disorder: The teacher discussed the child's issues with his parents. A place of egress; an outlet: a lake with no issue to the sea. Pathology A discharge, as of blood or pus. Pathology A lesion, wound, or ulcer producing such a discharge. Archaic Termination; close. To go or come out. See Synonyms at appear. To accrue as proceeds or profit: Little money issued from the stocks. To be born or be descended. To be circulated or published. To spring or proceed from a source. See Synonyms at stem1.