To select from a number of possible alternatives; decide on and pick out. To prefer above others: chooses the supermarket over the neighborhood grocery store. To determine or decide: chose to fly rather than drive. To make a choice; make a selection: was used to doing as she chose. choose up To choose players and form sides or teams for a game, such as baseball or softball. cannot choose but Can only do; cannot do otherwise: We cannot choose but to observe the rules.