What is acute? What is acute? Having a sharp point or tip.Keenly perceptive or discerning: "a raw, chilling and psychologically acute novel of human passions reduced to their deadliest essence” ( Literary Guild Magazine). See Synonyms at sharp.Reacting readily to stimuli or impressions; sensitive: His hearing was unusually acute. Of great importance or consequence; crucial: an acute lack of research funds. Extremely sharp or severe; intense: acute pain; acute relief. Medicine Having a rapid onset and following a short but severe course: acute disease. Medicine Afflicted by a disease exhibiting a rapid onset followed by a short, severe course: acute patients. Music High in pitch; shrill.Geometry Having an acute angle: an acute triangle.