Qu'est-ce qu'un bother? Qu'est-ce qu'un bother? To disturb or anger, especially by minor irritations; annoy. See Synonyms at annoy.To make agitated or nervous; fluster.To make confused or perplexed; puzzle. To intrude on without invitation or warrant; disturb.To give trouble to: a back condition that bothers her constantly. To take the trouble; concern oneself.To cause trouble.A cause or state of disturbance.Used to express annoyance or mild irritation.